Triclabendazole is an anthelmintic medication used in the treatment of infections caused by liver flukes, specifically Fasciola hepatica and Fasciola gigantica. These parasites are flatworms that primarily infect the liver and can cause significant damage if left untreated.
Triclabendazole is used in the treatment of fascioliasis, an infection caused by liver flukes. This condition occurs when humans ingest water or food contaminated with the infective stage of the parasite.
Triclabendazole works by disrupting the metabolism of the parasite, leading to its paralysis and death. It interferes with the function of tubulin, a protein essential for the structure and function of the parasite’s cells. This results in the disintegration of the parasite’s tegument and disruption of its normal physiological processes.
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